Synaptic plasticity after ischemic brain injury
10.3760/cma.j.issn.1673-4165.2023.04.014
- VernacularTitle:缺血性脑损伤后的突触可塑性
- Author:
Ruijie YANG
1
;
Dujuan SHA
Author Information
1. 南京医科大学附属鼓楼临床医学院全科医学科，南京 210008
- Keywords:
Ischemic stroke;
Brain ischemia;
Neuronal plasticity;
Synapses
- From:
International Journal of Cerebrovascular Diseases
2023;31(4):312-317
- CountryChina
- Language:Chinese
-
Abstract:
Ischemic stroke is a common disease of the nervous system, which is characterized by high incidence, recurrence, disability and mortality rate. The pathological mechanism of ischemic brain injury is complex. Synaptic plasticity injury is considered to be the earliest pathological change after cerebral ischemia, and regulating synaptic plasticity is one of the important mechanisms to promote the recovery of neurological function after stroke. This article reviews the advances in synaptic plasticity after ischemic brain injury, which provides theoretical basis for the development of neuroprotective drugs in the future.
