Progress of the central nervous system myelin sheath development and related diseases in children
10.3760/cma.j.issn.1673-4408.2023.08.010
- VernacularTitle:儿童中枢神经系统髓鞘发育及相关疾病研究进展
- Author:
Zhiyu WANG
1
;
Xuewen SU
Author Information
1. 内蒙古自治区人民医院儿科，呼和浩特 010010
- Keywords:
Children;
Central nervous system;
Myelin sheath;
Oligodendrocyte
- From:
International Journal of Pediatrics
2023;50(8):544-548
- CountryChina
- Language:Chinese
-
Abstract:
The myelin sheath of the central nervous system(CNS)is a multilayer lipid membrane with oligodendrocyte membrane surrounding the axon.The development of myelin sheath in children follows the corresponding laws of time and space, and this process of myelination is considered to be related to children′s proper behavior and function.The myelin sheath development of CNS in childhood is a multi-step and extremely complex process, and the integrity of myelin sheath plays a crucial role in shaping CNS function.At present, it has been found that many neurological diseases in children, such as multiple sclerosis, transverse myelitis and pediatric optic neuritis are closely related to myelin sheath abnormality.Therefore, this paper reviews the progress of myelin sheath development and related diseases in childhood, so as to provide a basis for clinical diagnosis and treatment of myelin sheath abnormalities.
