Advances in the levels of neurotransmitters associated with attention deficit hyperactivity disorder in children with tic disorders
10.3760/cma.j.issn.1673-4408.2023.07.013
- VernacularTitle:儿童抽动障碍共患注意缺陷多动障碍相关神经递质水平的研究进展
- Author:
Wanbing XU
1
;
Dan SUN
;
Zhisheng LIU
Author Information
1. 华中科技大学同济医学院附属武汉儿童医院神经内科 430016
- Keywords:
Tic disorders;
Tourette syndrome;
Attention deficit hyperactivity disorder;
Neurotransmitter
- From:
International Journal of Pediatrics
2023;50(7):482-486
- CountryChina
- Language:Chinese
-
Abstract:
Tic disorders(TD)including Tourette syndrome are childhood-onset neurodevelopmental disorders characterized by motor and/or vocal tics that commonly affect children′s physical and mental health.More than half of TD patients also have attention deficit hyperactivity disorder(ADHD). The pathogenesis of TD is not clear, and it is believed to be related to the abnormal level of neurotransmitters caused by the dysfunction of the cortical-striatal-thalamic-cortical circuitry, and the disorder of neurotransmitters is also related to the pathogenesis of ADHD, but the current research results on the level of neurotransmitters in TD with comorbid ADHD are controversial, and even some neurotransmitters show completely opposite changes in the two diseases.This paper reviews the research progress of neurotransmitters in children with TD co-suffering from ADHD in recent years, in order to provide ideas for exploring its pathogenesis.
