Application value of procalcitonin in neonatal sepsis
10.3760/cma.j.issn.1673-4408.2023.03.007
- VernacularTitle:降钙素原在新生儿败血症中的应用价值
- Author:
Fei LI
1
;
Wenjing SHI
Author Information
1. 上海交通大学医学院附属第六人民医院儿科 200233
- Keywords:
Procalcitonin;
Neonatal sepsis;
Diagnosis;
Antibiotic
- From:
International Journal of Pediatrics
2023;50(3):173-177
- CountryChina
- Language:Chinese
-
Abstract:
Procalcitonin(PCT), an important inflammatory suggestive marker of bacterial infection, has been widely used for the diagnosis of infectious diseases and guidance of antibiotic therapy in adults and children.Recent studies have shown that PCT, as a highly sensitive and specific inflammatory indicator, also has promising applications in the diagnosis and differential diagnosis, disease judgement, prognosis analysis, and antibiotic guidance of neonatal sepsis.Early PCT in neonates is characterized by physiological elevation, and it is important to understand the changing characteristics and influencing factors of PCT in neonates for an accurate clinical judgement of the disease.Therefore, we review the application value of PCT in neonatal sepsis.