Advances in relationship between the gut-lung axis and bronchopulmonary dysplasia
10.3760/cma.j.issn.1673-4408.2023.03.002
- VernacularTitle:肠-肺轴与支气管肺发育不良关系的研究进展
- Author:
Bowen WENG
1
;
Cheng CAI
Author Information
1. 上海市儿童医院 上海交通大学医学院附属儿童医院新生儿科 200062
- Keywords:
Infants, premature;
Bronchopulmonary dysplasia;
Gut-lung axis;
Intestinal microecology;
Microbiota
- From:
International Journal of Pediatrics
2023;50(3):150-153
- CountryChina
- Language:Chinese
-
Abstract:
Bronchopulmonary dysplasia(BPD), a common respiratory disease in premature infants, leads to poor long-term prognosis.The crosstalk between the gut and lung which can be mediated by microbiota is known as the gut-lung axis.Recently, an increasing amount of evidence has indicated that the gut microbiota is closely related to the pathogenesis of many respiratory diseases.The gut-lung axis affects the occurrence and development of BPD through microbiota translocation and regulation of immune pathways.At present, the relationship between the gut-lung axis and BPD is still in the research stage and exploring the potential association may help to search early markers and new therapies for BPD.In order to provide insights into preventing and treating BPD, this review describes the relationship between the gut-lung axis and BPD.
