Progress of the role and molecular mechanism of pyroptosis in leukemia
10.3760/cma.j.issn.1673-4408.2023.01.012
- VernacularTitle:细胞焦亡在白血病中的作用及分子机制研究进展
- Author:
Yanmin MA
1
;
Xiaocheng YIN
Author Information
1. 南华大学附属第一医院儿科，衡阳 421000
- Keywords:
Leukemia;
Pyroptosis;
Molecular mechanism
- From:
International Journal of Pediatrics
2023;50(1):57-60
- CountryChina
- Language:Chinese
-
Abstract:
Pyroptosis is a newly discovered programmed cell death in recent years.The researches show that pyroptosis plays an important role in many diseases.Leukemia is a malignant hematopoietic stem cell disease, which seriously threatens the health and life of children.Numerous studies have shown that pyroptosis is associated with the occurrence and development of leukemia, and elucidation the mechanism of pyroptosis in leukemia will provide a new method of clinical treatment.In this review, in order to enhance the understanding of the mechanism of pyroptosis and provide some ideas for the treatment of leukemia, the molecular mechanism of pyroptosis and its role in leukemia are reviewed.
