Efficacy Evaluation of Apparent Diffusion Coefficient in the Treatment of Uterine Fibroid by Magnetic Resonance Guided Focused Ultrasound Surgery
10.13471/j.cnki.j.sun.yat-sen.univ（med.sci）.2023.0520
- VernacularTitle:表观弥散系数对磁共振引导聚焦超声术治疗子宫肌瘤效果的评估
- Author:
Xue-wei ZENG
1
;
Shou-guo ZHOU
1
;
Yao-qu HUANG
1
;
Zi-hua WANG
1
;
Ya-nan HE
1
;
Hua-yi HUANG
1
;
Juan WANG
1
Author Information
1. Department of Radiology， Foshan Hospital of Traditional Chinese Medicine， Foshan 528000， China
- Publication Type:Journal Article
- Keywords:
magnetic resonance imaging;
apparent diffusion coefficient;
magnetic resonance guided focused ultrasound surgery;
uterine fibroid;
ablation
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2023;44(5):863-869
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo assess the value of apparent diffusion coefficient （ADC） in the treatment of uterine fibroid using magnetic resonance guided focused ultrasound surgery （MRgFUS）. MethodsThe MRI and clinical data of 56 patients with uterine fibroid before， at 3 and 6 months after MRgFUS treatment， at Foshan Hospital of Traditional Chinese Medicine from December 2018 to October 2022， were retrospectively analyzed. The correlation between the ADC value and lesion volume， symptoms severity score （SSS） and uterine fibroid symptoms quality of life questionnaire （UFS-QOL） were analyzed. ANOVA was used to compare the differences in related parameters before and after treatment， and Pearson’s method was performed to analyze data correlation. ResultsThere were significant differences in ADC value ［（1.11±0.13）， （1.84±0.09）， （2.12±0.24），×10-3/（mm2/s）］， lesion volume （102±35.30， 56.70±18.88， 46.93±18.99，cm3）， SSS （36.73±11.74， 21.77±10.21， 17.66±9.30） and UFS-QOL score （59.05±17.48， 76.54±16.50， 82.46±12.37） between before treatment and each time point after treatment （F value was 557.837， 73.589， 53.976 and 37.606， respectively， all P<0.05）. The ADC values were negatively correlated with lesion volume and SSS， and positively correlated with UFS-QOL score， with correlation coefficients of -0.586， -0.630 and 0.592， respectively （all P<0.05）. ConclusionThe ADC value has clinical significance for the treatment of uterine fibroid using MRgFUS.
