Study on chemical constituents of Hippocampus trimaculatus Leach
10.12206/j.issn.2097-2024.202212032
- VernacularTitle:三斑海马的化学成分研究
- Author:
Fangliang QIAO
1
;
Tianshuang XIA
1
;
Chengzhong ZHANG
2
;
Yiping JIANG
1
;
Hailiang XIN
1
Author Information
1. Department of Pharmacognosy.
2. Department of Chinese Medicine Identification, School of Pharmacy, Naval Medical University, Shanghai 200433, China.
- Keywords:
Hippocampus trimaculatus Leach;
chemical constituents;
extraction and separation;
structure identification
- From:
Journal of Pharmaceutical Practice
2023;41(9):540-543
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the chemical constituents of Hippocampus trimaculatus Leach. Methods After extracted with ethanol, Hippocampus trimaculatus Leach was isolated and purified by silica gel column chromatography, Sephadex LH-20 gel column chromatography, and reversed-phase C18 column chromatography. The structures of compounds were identified by physical and chemical properties, spectral data and literature comparison. Results Eight compounds were isolated from Hippocampus trimaculatus Leach and identified as L-phenylalanine (1), alanine (2), inosine (3), cholesterol (4), N-acetyltyramine (5), uracil (6), D-mannitol (7), tetrodoine (8), respectively. Conclusion Compounds 5, 7, 8 are isolated from Hippocampus trimaculatus Leach for the first time.
