Research progress on use of common packaging forms of injections
10.12206/j.issn.2097-2024.202204103
- VernacularTitle:注射剂常用包装形式研究使用进展
- Author:
Min WANG
1
;
Suping ZHOU
1
;
Shuai ZHANG
1
;
Boyang WANG
1
;
Cang CHU
1
Author Information
1. Administration for Drug and Instrument Supervision and Inspection of PLAJLSF, Beijing 100071, China.
- Keywords:
injections;
packaging forms;
research progress
- From:
Journal of Pharmaceutical Practice
2023;41(9):528-533
- CountryChina
- Language:Chinese
-
Abstract:
Objective To provide theoretical reference and practical basis for accurately choosing the suitable packaging forms for different Injections. Methods Based on the raw materials in the common packaging forms of injections, the research and application progress on different packaging forms for injections were reviewed by analyzing the characteristics and technical requirements of different packaging forms, and the current registration information of pharmaceutical packaging materials in the Center for Drug Evaluation, NMPA were introduced. Results For preparations with small single-dose and low-cost, the ampoules or injection vials could be chosen. Powder injections are usually packaged in injection vials. For rescue medicines and valuable medicines, the pre-filled syringes could be chosen. For chronic disease treatment drugs (such as insulin) that require long-term injection, or some injections for emergency use, a pen-type syringe package that patients can inject themselves could be used. Neutral glass packaging or plastic packaging should be used for some acidic or alkaline. Conclusion The drug manufacturers should comprehensively consider the physicochemical properties of drugs, the performance of packaging raw materials, compatibility test results, price-cost, and convenience in carrying and use when choosing the appropriate packaging form to ensure the quality, safety, and effectivity of drugs.
