Effects of Autophagy-related Genes and Signal Pathways on Occurrence and Development of Oral Tumors
10.3971/j.issn.1000-8578.2021.20.1377
- VernacularTitle:自噬相关基因及信号通路在口腔肿瘤发生发展中的影响
- Author:
Rui XUE
1
;
Jiping GAO
;
Xiaoru YAN
;
Guoqiang XU
;
Guohua SONG
Author Information
1. Experimental Animal Center of Shanxi Medical University, Key Laboratory of Experimental Animals and Animal Models of Human Diseases in Shanxi Province, Taiyuan 030001, China
- Publication Type:Research Article
- Keywords:
Autophagy-related gene;
Signaling pathway;
Oral carcinoma
- From:
Cancer Research on Prevention and Treatment
2021;48(5):514-518
- CountryChina
- Language:Chinese
-
Abstract:
Autophagy is a highly conservative cellular self-protective behavior dependent on lysosomes, and can be used as an important factor in promoting or preventing cancer, and its effect is related to the type and development of tumors. A full understanding of autophagy pathway is helpful to improve the diagnosis and treatment of tumors. Studies have shown that autophagy is closely related to the occurrence and development of oral tumors. Autophagy-related genes and signal pathways play a dual regulatory role on oral tumors. This article reviews the latest progress in the regulatory mechanism and therapeutic effect of autophagy on oral tumors.
