Diagnostic Value of mDIXON Quant MRI for Vertebral Metastasis
10.3971/j.issn.1000-8578.2021.21.0193
- VernacularTitle:磁共振改良DIXON定量技术在椎体转移瘤中的诊断价值
- Author:
Jia ZHANG
1
;
Haibo TAO
;
Yingying DING
;
Mei LI
;
Shiyun SUN
;
Manzhu LI
;
Kun LI
Author Information
1. Department of Radiology, The Third Affiliated Hospital of Kunming Medical University, Kunming 650118, China
- Publication Type:Research Article
- Keywords:
Vertebral metastasis;
MRI;
Modified dixon quantification (mDIXON Quant);
Fat fraction
- From:
Cancer Research on Prevention and Treatment
2021;48(9):888-892
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the diagnostic efficacy of mDIXON Quant for vertebral metastasis. Methods We retrospectively analyzed MRI images of 152 patients with clinically diagnosed malignant tumors and vertebral metastases. Scanning sequence included T1WI, STIR, mDIXON Quant and enhanced T1WI. We compared the diagnostic efficiency between T1WI and FF images for vertebral metastases. FF values between normal vertebral body and vertebral metastases were quantitatively compared, and the diagnostic efficacy of FF value was evaluated by ROC curve. Results The sensitivity, false positive rate, false negative rate, negative predictive value and accuracy of FF images in the diagnosis of vertebral metastases were all higher than those of T1WI images. The FF value of vertebral metastasis was significantly lower than that of normal vertebral body (Z=-21.792, P < 0.05), and the area under ROC curve was 0.987 and the cutoff value was 9.87%. The diagnostic sensitivity and specificity of vertebral metastasis were 99.6% and 92.0%. Conclusion mDIXON Quant can quantitatively determine the fat content of vertebral metastasis and has a high diagnostic efficiency for vertebral metastases.
