Risk of Primary Lung Cancer in Breast Cancer Patients: A Systematic Review and Meta-analysis
10.3971/j.issn.1000-8578.2021.20.1430
- VernacularTitle:乳腺癌患者原发性肺癌发生风险的系统评价和Meta分析
- Author:
Jinzhao LIU
1
;
Xiangmei ZHANG
;
Yarong ZHOU
;
Yunjiang LIU
Author Information
1. Department of Breast Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China
- Publication Type:Research Article
- Keywords:
Breast cancer;
Lung cancer;
Systematic review;
Meta-analysis;
Standardized incidence raio
- From:
Cancer Research on Prevention and Treatment
2021;48(7):733-737
- CountryChina
- Language:Chinese
-
Abstract:
Objective To systematically evaluate the risk of primary lung cancer in breast cancer patients. Methods A computer-based search was conducted for the English literatures about the risk of primary lung cancer in breast cancer patients in Medline, Scopus and Embase databases. Two researchers independently screened the literatures, extracted the data and assessed the risk of bias. The statistical analysis was performed using the Stata 15.5 software. Results A total of 7 references were included, and the overall risk of primary lung cancer in female breast cancer patients was slightly higher than that in the general population (SIR: 1.18, 95%CI: 1.09-1.27). Subgroup analysis showed that the risk of lung cancer was significantly increased in women aged < 50 years after diagnosis of breast cancer (SIR: 1.99, 95%CI: 1.48-2.69). Conclusion Compared with the general population, the risk of primary lung cancer is increased in female breast cancer patients, especially in young women with breast cancer.
