Research Progress of Glucose Metabolism Reprogramming in Basic Research and Clinical Diagnosis and Treatment of Tumor
10.3971/j.issn.1000-8578.2021.20.1425
- VernacularTitle:葡萄糖代谢重编程在肿瘤基础研究及临床诊疗中的研究进展
- Author:
Yuan JIANG
1
;
Ya CHEN
;
Yangyang XIE
;
Xinyu HUANG
;
Jian ZHAO
;
Beibei LIANG
Author Information
1. School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China
- Publication Type:Research Article
- Keywords:
Malignant tumor;
Glucose metabolism reprogramming;
Key target
- From:
Cancer Research on Prevention and Treatment
2021;48(6):635-641
- CountryChina
- Language:Chinese
-
Abstract:
Tumors provide materials and energy for themselves through glucose metabolic reprogramming to meet the needs of their rapid growth. Studies have shown that a variety of metabolic enzymes and signal molecules involved in glucose metabolism play an important role in tumorigenesis and development, and are considered to be important targets for the diagnosis and treatment of malignant tumors. The detection technology based on tumor glucose metabolism has been widely used in basic research and clinical diagnosis and treatment of tumor. This paper summarizes the characteristics, driving factors and key regulatory targets of tumor glucose metabolism, and the detection techniques and functions of tumor glucose metabolism from the aspects of basic medical research and clinical diagnosis and treatment.
