Effect of Short-term Complications After D2 Radical Gastrectomy on Long-term Survival Rate of Gastric Cancer Patients
10.3971/j.issn.1000-8578.2021.20.1390
- VernacularTitle:胃癌D2根治术后短期并发症对患者远期生存率的影响
- Author:
Penghang LIN
1
;
Chunlin LIN
;
Qin WANG
;
Ruofan HE
;
Hui CHEN
;
Yongjian HUANG
;
Shugang YANG
;
Jianxin YE
;
Guangwei ZHU
Author Information
1. Department of Gastrointestinal Surgery 2 Section, The First Hospital Affiliated to Fujian Medical University, Institute of Abdominal Surgery, Key Laboratory of Accurate Diagnosis and Treatment of Cancer, Fuzhou 350005, China
- Publication Type:Research Article
- Keywords:
D2 radical gastrectomy;
Short-term postoperative complication;
Survival analysis;
Long-term survival rate;
Propensity score matching method
- From:
Cancer Research on Prevention and Treatment
2021;48(6):625-630
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of short-term complications after D2 radical gastrectomy on long-term survival rate of gastric cancer patients. Methods A retrospective case-control study was conducted on 421 patients with gastric cancer who underwent D2 radical gastrectomy. According to the short-term postoperative complications, they were divided into experimental group (complication group, n=76) and control group (without complication group, n=345). In order to reduce the selection bias, the long-term survival rate of the two groups was tested by Kaplan-Meier survival analysis method after balancing the variables by propensity score matching (PSM). Log rank method was used for univariate analysis and Cox multivariate analysis was used for prognostic factors. Results There was no significant difference in long-term survival rate between the experimental group and the control group (P > 0.05). Histological type, lymph node metastasis rate and pTNM stage were independent risk factors for long-term survival. Conclusion The short-term complications after D2 radical gastrectomy have no significant impact on the long-term survival rate of gastric cancer patients, but it has certain clinical significance to actively prevent and control complications.
