Metabolic Syndrome and Risk of Gastric Cancer: A Meta-analysis

VernacularTitle:代谢综合征与胃癌发病风险的Meta分析
Author: Tong LIANG ¹ ; Huajie LIU ; Mingxu DA
Author Information

1. The First Clinical Medical College, Gansu University of Chinese Medicine, Lanzhou 730101, China
Publication Type:Research Article
Keywords: Metabolic syndrome; Gastric cancer; Association; Meta-analysis
From: Cancer Research on Prevention and Treatment 2021;48(3):268-273
CountryChina
Language:Chinese
Abstract: Objective To evaluate the relation between metabolic syndrome (MetS) and gastric cancer (GC) based on a meta-analysis. Methods The case-control studies about the relation between MetS and GC were retrieved from CNKI, WanFang Data, VIP, CBM, Web of Science, The Cochrane Library and PubMed database. The retrieval time was from inception to June, 2020. Two researchers independently screened the literatures, extracted the data and evaluated the quality of the included studies. The meta-analysis of the included literatures was conducted by the Stata 12.0 software. Results A total of six literatures, involving 43617 participants, were included. The results of meta-analysis showed that there was no statistically significant difference between GC and non-GC groups in the risk of hyperglycemia (OR=1.24, 95%CI: 0.59-2.61), hypertension (OR=1.40, 95%CI: 0.60-3.25) or MetS (OR=0.79, 95%CI: 0.44-1.39), respectively. Conclusion MetS may not be related to the risk of GC.