Research Progress on Energy Metabolism and Radiosensitivity of Glioma
10.3971/j.issn.1000-8578.2021.20.0668
- VernacularTitle:胶质瘤能量代谢与放射敏感度的研究进展
- Author:
Fuling MOU
1
;
Jiawei ZHONG
;
Pengfei SUN
Author Information
1. The Second Clinical Medical College, Lanzhou University, Lanzhou 730030, China
- Publication Type:Research Article
- Keywords:
Glioma;
Energy metabolism;
Warburg effect;
Radiosensitivity;
CircRNAs
- From:
Cancer Research on Prevention and Treatment
2021;48(2):201-204
- CountryChina
- Language:Chinese
-
Abstract:
Radiotherapy is an important auxiliary treatment for glioma. Although comprehensive treatment of glioma has made some progress in recent years, the prognosis is still poor. How to improve the radiosensitivity of glioma is one of the hot spots in current glioma research. The changes of energy metabolism in gliomas promote malignant progression and resistance to chemoradiotherapy, but the exact mechanism is still unclear. This paper reviews the research progress of energy metabolism in gliomas and its relation with radiosensitivity of gliomas, in order to lay a foundation for further exploration of improving radiosensitivity of gliomas.