Role of Exosome in Microenvironment of Hematological Malignancies and Its Diagnostic and Therapeutic Potential
10.3971/j.issn.1000-8578.2021.20.0617
- VernacularTitle:外泌体在血液肿瘤微环境中的作用及其诊治意义
- Author:
Yingyu NAN
1
;
Xuan YAO
;
Zhong YANG
Author Information
1. Department of Hematological Oncology, Chongqing University Cancer Hospital, Chongqing 400038, China
- Publication Type:Research Article
- Keywords:
Exosome;
Microenvironment;
Hematological malignancies;
Diagnosis;
Therapy
- From:
Cancer Research on Prevention and Treatment
2021;48(1):93-97
- CountryChina
- Language:Chinese
-
Abstract:
Exosome, a major component of extracellular vesicles, is an important media for intercellular communications under physiological conditions. In a variety of hematological malignancies researches, it has been demonstrated that exosome acts as the key carrier for interactions among the components of the bone marrow microenvironment. Due to its widespread existence and containing specific nucleic acid and protein molecules, the importance of exosome as a potential biomarker and therapeutic target/carrier in the diagnosis and treatment of hematological malignancies has been attracting more attention in the past few years.
