Association between ABO Blood Groups and Severity of Dyspepsia in Gunungsitoli, Indonesia
https://doi.org/10.47895/amp.vi0.1492
- Author:
OK Yulizal
1
;
Gontar Alamsyah Siregar
2
;
Lukman Hakim Zain
2
;
Leonardo Basa Dairy
2
Author Information
1. Department of Internal Medicine, Faculty of Medicine, Universitas Prima Indonesia, Medan, Indonesia
2. Division of Gastroentero-Hepatology, Department of Internal Medicine, Haji Adam Malik Central General Hospital, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia
- Publication Type:Journal Article
- Keywords:
Dyspepsia symptoms;
PADYQ score;
Porto Alegre Dyspeptic Symptoms Questionnaire
- MeSH:
ABO Blood-Group System
- From:
Acta Medica Philippina
2022;56(7):73-78
- CountryPhilippines
- Language:English
-
Abstract:
Background:Human blood groups may play a key role in various human diseases. An association has been found between ABO blood groups and both infectious and non-infectious diseases of the gastrointestinal tract and other organs. Dyspepsia is one of the most common encountered gastrointestinal complaints.
Aims:To investigate the association between ABO blood groups and severity of dyspepsia symptoms in a specific ethnic group.
Study Design:Cross-sectional study.
Methods:Consecutive adult Nias tribe dyspepsia outpatients in the General District Hospital, Gunungsitoli Nias,Indonesia, were interviewed using a structured questionnaire between May–June 2018. The severity of dyspepsia was assessed with the Porto Alegre Dyspeptic Symptoms Questionnaire (PADYQ) scoring instrument. ABO blood groups were determined by a standard direct agglutination test. Upper gastrointestinal endoscopy was performed in all participants. Data were statistically analyzed using statistical software. P value less than 0.05 was considered as statistically significant.
Results:Of 66 patients, 54.5% were males, with median age of 47 years (range, 23–67). Majority of the participants had blood group O (48.5%). The most encountered dyspepsia symptom was epigastric pain (66.7%). Participants with blood group type B had significantly more severe dyspepsia symptoms based on total PADYQ score (p=0.017). Participants with blood group type O were more prone to epigastric pain (p=0.015), while blood group type B to bloating (p=0.01) and early satiation (p=0.02).
Conclusion:In outpatients from the Nias tribe with dyspepsia, those with blood group type B had more severe dyspepsia symptoms.
- Full text:1492-Article Text-26917-2-10-20220428.pdf
