Didangtang: A Review
10.13422/j.cnki.syfjx.20231394
- VernacularTitle:抵挡汤的研究进展
- Author:
Xize WU
1
;
Jian KANG
1
;
Yue LI
2
;
Jiaxiang PAN
2
Author Information
1. Liaoning University of Traditional Chinese Medicine(TCM),Shenyang 110847,China
2. The First Affiliated Hospital of Liaoning University of TCM,Shenyang 110032,China
- Publication Type:Journal Article
- Keywords:
Didangtang;
clinical application;
mechanism;
research progress
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2023;29(20):230-238
- CountryChina
- Language:Chinese
-
Abstract:
As one of the classic prescriptions of traditional Chinese medicine, Didangtang is an effective prescription for breaking and expelling blood stasis. It was considered that Didangtang damage the healthy qi and contained toxic Chinese medicinal materials such as leeches and gadflies, and thus it was rarely used. However, as the attention to classic prescriptions increases, Didangtang has been widely used in clinical practice and demonstrated definite efficacy in treating diabetes mellitus and its complications, malignant tumors, Alzheimer's disease, stroke, renal diseases, cardiovascular diseases, peripheral vascular diseases, gynecological disease, and male diseases according to the disease location, pathogenesis, symptoms, and pharmacological effects. Didangtang has the effects of mitigating insulin resistance, improving microvascular and peripheral vascular circulation, delaying diabetic macrovascular lesions, preventing vascular fibrosis, improving immunity, inhibiting tumor growth, protecting the brain tissue, nerve cells, vascular endothelial function, and kidney, reducing inflammation, and delaying aging. This paper summarizes the clinical application of Didangtang and initially explores the underlying mechanism.