Study Protocol of a Mixed-Methods Study to Develop and Validate the Malaysian Anti-Hypertensive Agents Non-Adherence Scale in Hypertensive Patients
https://doi.org/10.47836/mjmhs.18.6.42
- Author:
Sheng-Qian Yew
1
;
Ahmad Iqmer Nashriq Bin Mohd Nazan
1
;
Kit-Aun Tan
2
Author Information
1. Department of Community Health, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
2. Department of Psychiatry, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
- Publication Type:Other Types
- Keywords:
Hypertension, Medication adherence, Mixed-methods
- From:Malaysian Journal of Medicine and Health Sciences
2022;18(No.6):332-339
- CountryMalaysia
- Language:English
-
Abstract:
Introduction: Domains of adherence and non-adherence to hypertensive medications have not been extensively
documented in Malaysia due to the absence of theoretically driven and culturally appropriate measurement tools,
leading to a poor understanding of the adherence and underlying factors. We aim to identify these domains in Malaysian hypertensive patients and subsequently apply the findings to develop and validate the Malaysian Anti-Hypertensive Agents Non-Adherence Scale (MAANS). Methods: This study has an exploratory mixed-methods design.
In Phase 1, we will recruit hypertensive patients from two health clinics to participate in a semi-structured interview.
Recruitment of participants will terminate once thematic saturation is achieved. Coding and thematic analyses will
be performed to identify the domains of adherence and non-adherence to anti-hypertensive medications. In Phase
2, based on the domains generated from Phase 1, we will develop the Malaysian Anti-Hypertensive Agents Non-Adherence Scale (MAANS). Four hundred hypertensive patients will be randomly selected. Data from 200 participants
(serving as the calibration sample) will be subjected to exploratory factor analysis while data from additional 200
participants (serving as the validation sample) will be subjected to confirmatory factor analysis. Factor structure,
predictive validity, and reliability of the MAANS will be statistically tested. Discussion: With the presence of the
MAANS, health care providers can gather crucial information regarding barriers and facilitators to hypertensive
treatment adherence and design effective health promotion programmes to reduce complications of uncontrolled
hypertension. Trial registration: Ethical approval is granted by the Medical Research Ethics Committee, Ministry of
Health, Malaysia (NMRR-18-3251-44694).
- Full text:11.2022my1392.pdf
