Biomechanical Parameters for Carotid Risk Assessment: A Review
10.16156/j.1004-7220.2023.03.28
- VernacularTitle:用于颈动脉风险评估的生物力学参数研究综述
- Author:
Yuhen YANG
1
,
2
,
3
;
Shuqi REN
1
,
2
,
3
;
Zengsheng CHEN
1
,
2
,
3
;
Yubo FAN
1
,
2
,
3
;
Anqiang SUN
1
,
2
,
3
;
Xiaoyan DENG
1
,
2
,
3
Author Information
1. Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education
2. . Beijing Advanced Innovation Center for Biomedical Engineering
3. School of Biological Science and Medical Engineering, Beihang University
- Publication Type:Journal Article
- Keywords:
carotid;
atherosclerosis;
computational simulation
- From:
Journal of Medical Biomechanics
2023;38(3):E615-E620
- CountryChina
- Language:Chinese
-
Abstract:
Carotid is in a high risk of atherosclerosis due to its special geometric features and complex flow characteristics. Various biomechanical parameters are practical tools for carotid risk assessment. It has beenwidely accepted that oscillatory low shear environment promotes plaque formation. Based on this, more and more biomechanical indexes have been proposed, such as time-average wall shear stress, oscillatory shear index, relative residence time and so on. In this paper, multiple biomechanical parameters were introduced from the perspectives of shear stress and its temporal and spatial variation, turbulence, platelet transport and activation, stress concentration in vascular wall, etc. The development trend of biomechanical parameters related to carotid artery risk assessment was also analyzed, so as to provide the theoretical basis for more comprehensive and rapid carotid risk assessment