Effects of Human Postures on Flow Characteristics in Iliac Vein Compression Syndrome
10.16156/j.1004-7220.2023.03.12
- VernacularTitle:人体姿态对髂静脉压迫综合征血流特性影响
- Author:
Chaoqun LI
1
;
Yanqing ZHAN
2
;
Zhongming WANG
1
;
Yongxin GAO
1
;
Peng QIU
3
;
Cheng YAO
1
Author Information
1. College of Civil Engineering, Hefei University of Technology
2. Department of General Surgery, North District of First Affiliated Hospital of Anhui Medical University,Anhui Provincial Public HealthClinical Center
3. Department of Vascular Surgery,Shanghai Ninth People′ s Hospital,Shanghai Jiao Tong University School of Medicine
- Publication Type:Journal Article
- Keywords:
iliac vein compression syndrome;
numerical simulation;
porous media;
human postures
- From:
Journal of Medical Biomechanics
2023;38(3):E507-E513
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate effects of human postures on flow characteristics of iliac vein compression syndrome. Methods The numerical model of iliac vein was reconstructed from CT images of a typical patient with pelvic-type iliac vein compression syndrome with collateral veins. Based on the computational fluid dynamics method, the non-Newtonian model and the porous media model were adopted to describe effects of abnormal structures on blood flow and acquire the wall shear stress and pressure of iliac vein. The discrete phase model was used to study the residence conditions of erythrocytes under three human postures. Results The pressure gradient at two ends of the compressive region was lowest under lying state, while the iliac vein showed a high pressure under sitting and walking states. The local maximum wall shear stresses under three postures were found at narrow segment of the collateral vein and convergence region of two flows of right iliac vein. The maximum shear stress was largest under lying state and smallest under sitting state. The blood residence time of 52.2 s in the left iliac vein was the longest under sitting state. The residence time of 14.8 s was shortest under lying state. The blood residence time was 23.8 s under walking state. Conclusions Porous media model used to simulate the effect of abnormal structures was highly consistent with the angiography data. The venous hypertension under sitting and walking states was consistent with the clinical results, and the lying state could relieve the hypertensive condition. In terms of wall shear stress and blood residence time in iliac vein, the continual change between three human postures would cause endothelial damage and blood flow stasis alternately, thus increase the risk of thrombosis.
