Pretreatment Effects of Cutting Balloon on Coronary Artery Calcification Based on Finite Element Analysis
10.16156/j.1004-7220.2023.03.11
- VernacularTitle:基于有限元分析切割球囊对冠状动脉钙化病变 预处理效果
- Author:
Jiasong LI
1
;
Hongshua CAO
1
;
Meng LI
1
;
Lixia SHU
2
;
Changyan LIN
1
,
3
Author Information
1. Biomedical Engineering Research Laboratory, Beijing Anzhen Hospital, Capital Medical University
2. Institute of Cardiopulmonary and Vascular Diseases, Beijing Anzhen Hospital, Capital Medical University
3. Key Laboratory of Biomechanics, Capital Medical University
- Publication Type:Journal Article
- Keywords:
cutting balloon;
coronary artery calcification;
calcified plaque;
calcification fracture;
virtual stentimplantation
- From:
Journal of Medical Biomechanics
2023;38(3):E500-E506
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigates the applicability of cutting balloon in the pretreatment of superficial coronary artery calcified lesions, so as to decrease the occurrence of serious consequences in the treatment of calcified lesions. Methods The effect of cutting balloon on calcified plaques with different curvatures, thickness, and length was analyzed using the finite element method, with normal balloon as a control. The thickness of calcified plaque was set to 0.3 mm and 0.4 mm, and the length was set to 2 mm and 4 mm. The calcification degree was set to 120°, 180°, 270°and 360° according to the intravenous ultrasound (IVUS) calcification severity grading, with a total of 16 types of calcified plaques. The brittle fracture module was used to simulate calcification fracture of calcified plaques, and virtual stent implantation was carried out based on pretreatment simulation. The effect of pretreatment was evaluated by calcification fracture condition and stent roundness. Results For superficial calcification lesions, in lesions less than 120°, the balloon could not remove the calcification plaque obstruction, and the stent roundness rate was 82.75%. In 180° calcified lesions with thickness of less than 0.3 mm, the calcification was broken by cutting balloon under 1 215.9 kPa expansion pressure, and the post-stent roundness rate was 74.42%; normal balloon could not cause calcification fracture under safe expansion pressure (1 418.55 kPa). In 270°calcified lesions with thickness less than 0.3 mm, the normal balloon produced 3 fractures under 1 013.25 kPa expansion pressure. The cutting balloon produced 2 fractures under 1 013.25 kPa expansion pressure, and the balloon could not fracture the circular calcified lesions with thickness of 0.3 mm. Conclusions Cutting balloon is recommended for 180°calcified lesions with thickness less than 0.3 mm, the normal balloon is recommended for 270°calcified lesions, and balloon pretreatment is not recommended for annular lesions with thickness greater than 0.3 mm.
