Effect and prognosis of nimodipine on the patients with severe traumatic brain injury

VernacularTitle:尼莫地平对重型脑损伤患者疗效及预后的影响
Author: Jian-hong ZHANG ; Jian-zhong FAN ; Ai-wen DENG
Publication Type:Journal Article
Keywords: traumatic brain injury, nimodipine, treatment, prognosis
From: Chinese Journal of Rehabilitation Theory and Practice 2002;8(9):537-538
CountryChina
Language:Chinese
Abstract: ObjectiveTo observe the therapeutic effect and prognosis of nimodipine on severe traumatic brain injury. Methods64 patients with severe traumatic brain injury were divided into the nimodipine group(32 cases) and the routine treatment group(32 cases). The Glasgow Coma Scale(GCS) was assessed before and after the treatment. The Activities of Daily Living(ADL) and cognitive ability were evaluated in clear-headed patients. After 6 months follow-up, the Glasgow Outcome Scale (GOS), Bathel index and Mini Mental State Examination (MMSE) score were carried on.ResultsIn both of the two groups, GCS score were increased distinctively after treatment. The MMSE score in nimodipine group was higher than that of routine treatment group. There was no statistic difference in GOS and ADL between two groups after 6 months, but MMSE in nimodipine group was higher than that of routine treatment group. Conclusions Nimodipine could be helpful in cognitive function. The prognosis of severe traumatic brain injury lied on the degree of cerebral damage.