Portal vein aneurysm after liver transplantation: report of two cases and literature review
10.3969/j.issn.1674-7445.2023105
- VernacularTitle:肝移植术后门静脉瘤2例并文献复习
- Author:
Hongqiang ZHAO
1
;
Cao’er DONG
1
;
Yucheng HOU
1
;
Guangdong WU
1
;
Xuan TONG
1
;
Ang LI
1
;
Lihan YU
1
;
Qian LU
1
;
Guangxun XU
1
;
Hong CHEN
1
;
Rui TANG
1
Author Information
1. Hepatobiliary Pancreatic Center, Beijing Tsinghua Changgung Hospital Affiliated to Tsinghua University, Tsinghua University School of Clinical Medicine, Beijing 102218, China.
- Publication Type:OriginalArticle
- Keywords:
Portal vein aneurysm;
Liver transplantation;
Portal vein thrombosis;
Portal hypertension;
Transjugular intrahepatic portosystemic shunt (TIPS);
Liver graft failure;
Rejection;
Liver retransplantation
- From:
Organ Transplantation
2023;14(5):708-713
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the diagnosis and treatment experience of portal vein aneurysm after liver transplantation. Methods Clinical data of two recipients with portal vein aneurysm after liver transplantation were retrospectively analyzed. Clinical features, diagnosis, treatment and prognosis were summarized based on literature review. Results Both two cases were diagnosed with intrahepatic portal vein aneurysm complicated with portal vein thrombosis and portal hypertension after liver transplantation. Case 1 was given with targeted conservative treatment and he refused to undergo liver retransplantation. Physical condition was worsened after discharge, and the patient eventually died from liver graft failure, kidney failure, lung infection, and septic shock. Case 2 received high-dose glucocorticoid pulse therapy, whereas liver function was not improved, and the patient was recovered successfully after secondary liver transplantation. Conclusions Long-term complication of portal vein aneurysm (especially intrahepatic type) after liver transplantation probably indicates poor prognosis. Correct understanding, intimate follow-up and active treatment should be conducted. Liver retransplantation may be a potential treatment regimen.
