Relationships between Antiretroviral Therapy Adherence with Personality Traits and Presence of Psychological Distress among Adults with Human Immunodeficiency Virus in Northwest Peninsular Malaysia: A Cross-Sectional Study
https://doi.org/10.47836/mjmhs.18.5.8
- Author:
Ming Ming Ng
1
;
Karniza Khalid
2
;
Amalina Anuar
2
;
Mohd Azhar Mohd Yasin
1
Author Information
1. Department of Psychiatry, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia
2. Clinical Research Centre, Hospital Tuanku Fauziah, Jalan Tun Abdul Razak, 01000 Kangar, Perlis, Ministry of Health Malaysia
- Publication Type:Journal Article
- Keywords:
Anti-retroviral agents, Anxiety, Depressive disorder, Personality, HIV infections, Malaysia
- From:Malaysian Journal of Medicine and Health Sciences
2022;18(No.5):47-54
- CountryMalaysia
- Language:English
-
Abstract:
Introduction: Treatment adherence with antiretroviral therapy (ART) and its related factors have hitherto been the
subject of clinical concern. However, research focusing on the relationships between ART adherence and the presence of psychological distress and selected personality traits have yet to be concluded. Therefore, our study aimed
to remedy this. Methods: A multicentre hospital-based cross-sectional study was conducted in northwest Peninsular
Malaysia on HIV outpatients given ART from July 1st, 2018, till April 31st, 2020. Participants were recruited via
purposive sampling. Data were collected through an interviewer-guided questionnaires: Hospital Anxiety and Depression Scale (HADS) and Zuckerman-Kuhlman personality test (ZKPQ-M-40-CC), and interviewer-guided Timeline
Follow-back (TLFB) for the assessment of adherence to ART. Results: A total of 229 patients completed the study.
Majority (n=220, 96.1%) were considered adherent to ART. Among those who were non-adherent, two (22.2%) had
anxiety disorder and five (55.6%) had depressive disorder. There was no significant association between treatment
adherence and the presence of anxiety nor depression. However, sociodemographic factors determined that age
group (p=0.033) and marital status (p=0.044) were significantly associated with treatment adherence. Multivariate
analysis determined that ‘Active’ personality trait increases the likelihood to better treatment adherence by 1.14
times (95% CI: 1.02, 1.28, p=0.018). Conclusion: We did not find any association between treatment adherence and
the presence of anxiety or depression. However, higher scores in ‘Active’ personality trait increases the likelihood of
better treatment adherence among adult HIV on ART.
- Full text:11.2022my1327.pdf
