Research progress in anti-reflux reconstructions and mechanism after proximal gastrectomy.
10.3760/cma.j.cn441530-20221227-00547
- Author:
Mao Jie ZHANG
1
;
Ze Kun XU
1
;
Liang ZONG
2
;
Jie WANG
3
;
Bo WANG
1
;
Shao Ming QI
3
;
Hong Niu WANG
1
;
Min NIU
3
;
Peng CUI
2
;
Wen Qing HU
2
Author Information
1. Graduate Department of Changzhi Medical College, Changzhi 046000, China.
2. Clinical Medical Research Center for Malignant Tumor (Esophagogastric Junction Cancer) ,Changzhi 046000, China Department of gastrointestinal Surgery, Changzhi People's Hospital Affiliated to Changzhi Medical College, Changzhi 046000, China.
3. Clinical Medical Research Center for Malignant Tumor (Esophagogastric Junction Cancer) ,Changzhi 046000, China.
- Publication Type:Journal Article
- MeSH:
Humans;
Stomach Neoplasms/surgery*;
Gastrectomy;
Gastroesophageal Reflux;
Esophagogastric Junction/surgery*;
Pylorus/pathology*
- From:
Chinese Journal of Gastrointestinal Surgery
2023;26(5):499-504
- CountryChina
- Language:Chinese
-
Abstract:
The electrophysiological activity of the gastrointestinal tract and the mechanical anti-reflux structure of the gastroesophageal junction are the basis of the anti-reflux function of the stomach. Proximal gastrectomy destroys the mechanical structure and normal electrophysiological channels of the anti-reflux. Therefore, the residual gastric function is disordered. Moreover, gastroesophageal reflux is one of the most serious complications. The emergence of various types of anti-reflux surgery through the mechanism of reconstructing mechanical anti-reflux barrier and establishing buffer zone, and the preservation of, the pacing area and vagus nerve of the stomach, the continuity of the jejunal bowel, the original gastroenteric electrophysiological activity of the gastrointestinal tract, and the physiological function of the pyloric sphincter, are all important measures for gastric conservative operations. There are many types of reconstructive approaches after proximal gastrectomy. The design based on the anti-reflux mechanism and the functional reconstruction of mechanical barrier, and the protection of gastrointestinal electrophysiological activities are important considerations for the selected of reconstructive approaches after proximal gastrectomy. In clinical practice, we should consider the principle of individualization and the safety of radical resection of tumor to select a rational reconstructive approaches after proximal gastrectomy.
