Progress in Development of Targeted Therapeutic Drugs for Acute Myeloid Leukemia
10.3971/j.issn.1000-8578.2023.22.1056
- VernacularTitle:急性髓系白血病的靶向治疗药物研发进展
- Author:
Xiaojun JI
1
;
Tingli ZHAO
;
Lei MIAO
;
Yaxuan SI
;
Jian WU
;
Dan XU
Author Information
1. Innovation Department of the Research Institute, Nanjing Chia Tai Tian Qing Pharmaceutical Co., Ltd, Nanjing 210046, China
- Publication Type:Research Article
- Keywords:
AML;
Targeted therapy;
Immunotherapy;
Drug progress
- From:
Cancer Research on Prevention and Treatment
2023;50(4):413-421
- CountryChina
- Language:Chinese
-
Abstract:
Targeted therapeutic drugs for acute myeloid leukemia (AML) are showing immense development, thereby laying a solid foundation for the precise treatment of AML patients. The paper reviews four types of targeted drugs that have progressed rapidly for AML treatment (by targeting genes or signaling-pathway alterations, targeting apoptosis-related pathways, targeting cell-surface antigens, and targeting immune-related substances). We look forward to the future development directions of targeted drugs, providing references for hematologists and developers of new drugs for AML.
