Frontier and Future of Immunotherapy for Pancreatic Cancer
10.3971/j.issn.1000-8578.2023.22.1290
- VernacularTitle:胰腺癌免疫治疗的前沿与未来
- Author:
Wence ZHOU
1
;
Hui ZHANG
;
Xin LI
;
Shi DONG
Author Information
1. Department of General Surgery, Lanzhou University Second Hospital, Lanzhou 730000, China
- Publication Type:Research Article
- Keywords:
Pancreatic neoplasms;
Immunotherapy;
Cancer vaccine;
PD-1
- From:
Cancer Research on Prevention and Treatment
2023;50(4):338-344
- CountryChina
- Language:Chinese
-
Abstract:
Pancreatic cancer remains as one of the most lethal malignancies. Resistance to conventional therapies has led to little improvement in the survival of pancreatic cancer patients over the past few decades. Immune-based treatment strategies for pancreatic cancer, such as immune-checkpoint inhibitors, therapeutic vaccines, and combination immunotherapies show promise. Many immunotherapies have been explored in clinical trials, but they have yet to show significant therapeutic effects. Nevertheless, immunotherapy is inevitably the future of pancreatic cancer cure. This article introduces the current research progress and bottlenecks of immunotherapy for pancreatic cancer and puts forward further optimization directions and solutions. We hope to provide a reference for the future use of immunotherapy for pancreatic cancer.
