miR-155-5p Expression, Function and Regulation in Tumors
10.3971/j.issn.1000-8578.2023.22.1026
- VernacularTitle:miR-155-5p在肿瘤中的表达、功能以及调控作用
- Author:
Ruizhe JIN
1
;
Dixian WANG
;
Qian ZHAO
;
Tiejun LIU
Author Information
1. Department of Stomatology, The Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China
- Publication Type:Research Article
- Keywords:
MicroRNA;
miR-155-5p;
Tumor;
Drug resistance;
Prognostic markers
- From:
Cancer Research on Prevention and Treatment
2023;50(3):309-315
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs (miRNAs) are a class of small, single-stranded non-coding RNAs that act as important regulators of gene expression and are involved in a number of important processes in life. A large number of studies have suggested that dysregulation of miRNA expression may be an important part of the mechanism of human tumorigenesis and progression. MiR-155-5p is mainly regarded as an oncomiR that acts on multiple target genes to participate in tumor progression, although it has been suggested to possess cancer growth suppressor effects. In this paper, we summarize the effects of miR-155-5p on cancer cell proliferation, invasion, migration, and drug resistance in various tumor types and elucidate its value as a possible potential marker in assisting diagnosis.
