Research Progress of Androgen/Androgen Receptor Signaling Pathway in Hepatocellular Carcinoma

VernacularTitle:雄激素/雄激素受体信号通路在肝细胞癌中的研究进展
Author: Ruihua WANG ¹ ; Shiliang CAI ; Donghong LIU ; Hongsen CHEN ; Guangwen CAO
Author Information

1. Department of Epidemiology, Jinan University, Guangzhou 510632, China
Publication Type:Research Article
Keywords: Androgen; Androgen receptor; Signaling pathway; Hepatocellular carcinoma
From: Cancer Research on Prevention and Treatment 2023;50(2):180-185
CountryChina
Language:Chinese
Abstract: Hepatocellular carcinoma (HCC) is a kind of primary liver cancer with a high mortality rate. In China, the incidence ratio in males to females with HCC is 2:1–5:1. The difference in sex hormone pathways between males and females and the interaction between androgen/androgen receptors and HBV can lead to an incidence difference between males and females with HCC. Hence, the androgen/androgen receptor oncogenic pathway in hepatocellular carcinoma has received considerable attention. This review mainly summarizes the recent research progress on the androgen/androgen receptor oncogenic pathway in hepatocellular carcinoma.