Progress on Tumor Infiltrating Lymphocytes in Immunotherapy and Prognosis Evaluation of Breast Cancer
10.3971/j.issn.1000-8578.2022.22.0332
- VernacularTitle:肿瘤浸润性淋巴细胞在乳腺癌预后评估及免疫治疗中的应用进展
- Author:
Chenchen HONG
1
;
Feng YAO
Author Information
1. Department of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China
- Publication Type:Research Article
- Keywords:
Breast cancer;
Tumor infiltrating lymphocytes;
Prognosis;
Immunotherapy
- From:
Cancer Research on Prevention and Treatment
2022;49(11):1180-1183
- CountryChina
- Language:Chinese
-
Abstract:
Female breast cancer has surpassed lung cancer as the most commonly diagnosed cancer in 2020. A large number of studies have proved that tumor infiltrating lymphocytes (TILs) are lethal to tumors and play an important role in identifying tumor antigens. Therefore, the application of TILs in clinical immunotherapy and prognosis assessment of breast cancer has attracted wide attention. In this review, the basic research progress and clinical application of TILs in different molecular types of breast cancer are reviewed, and the value of TILs in judging breast cancer prognosis and predicting the therapeutic effect of clinical immunotherapy is evaluated.
