Advances in Tumor-associated Macrophages in Cancer Radiotherapy
10.3971/j.issn.1000-8578.2022.22.0042
- VernacularTitle:肿瘤相关巨噬细胞在肿瘤放射治疗中的研究进展
- Author:
Zhuochao WU
1
;
Zhaohui HUANG
Author Information
1. Wuxi Cancer Institute, Affiliated Hospital of Jiangnan University, Wuxi 214062, China
- Publication Type:Research Article
- Keywords:
Tumor-associated macrophage;
Radiotherapy;
Tumor microenvironment;
Radiation dose
- From:
Cancer Research on Prevention and Treatment
2022;49(9):870-874
- CountryChina
- Language:Chinese
-
Abstract:
Tumor-associated macrophages (TAMs) are one of the most abundant immune cells in the tumor microenvironment. As a heterogenous cell population, TAMs usually affect tumor growth, metastasis, and therapeutic resistance. Currently, TAM has attracted wide attention as a promising therapy target for human cancers. As one of the basic treatments of malignant tumors, radiotherapy can regulate the phenotypes and functions of TAM. Meanwhile, TAM can affect the response of cancer cells to radiation. This paper reviews the research advances of TAM in cancer radiotherapy.
