Current Status of Immunotherapy in Neoadjuvant Therapy for Gastric Cancer
10.3971/j.issn.1000-8578.2022.21.1241
- VernacularTitle:免疫治疗在胃癌新辅助治疗中的研究进展
- Author:
Bojin CHEN
1
;
Xingyi HU
;
Jingwen ZHAO
;
Aihong ZHENG
Author Information
1. The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou 310014, China
- Publication Type:Research Article
- Keywords:
Gastric cancer;
Neoadjuvant therapy;
Immunotherapy;
Tumor microenvironment
- From:
Cancer Research on Prevention and Treatment
2022;49(7):727-732
- CountryChina
- Language:Chinese
-
Abstract:
The majority of diagnosed cases of gastric cancer are in the middle and late stages, while less than 10% of patients are diagnosed in the early stages in China. The standard treatment strategy for patients with progressive gastric cancer is surgery combined with postoperative adjuvant therapy or preoperative neoadjuvant followed by surgery combined with postoperative adjuvant therapy. Immunotherapy is now recognized as an innovative approach for cancers. It is worth exploring how to best use immunotherapy in neoadjuvant therapy to achieve better clinical benefit. Therefore, this paper reviews the progress of immunotherapy in neoadjuvant therapy for GC. Further studies and the understanding of immune system function by neoadjuvant therapy combined with immunotherapy will help to improve the treatment of gastric cancer.
