Research Progress on Relation Between BTBP1 and Tumor Progression and Treatment
10.3971/j.issn.1000-8578.2022.21.1179
- VernacularTitle:PTBP1与肿瘤发展和治疗关系的研究进展
- Author:
Tong XIN
1
;
Yue SUN
;
Jing HU
Author Information
1. The Fourth Department of Medical Oncology, Harbin Medical University Cancer Hospital, Harbin 150081, China
- Publication Type:Research Article
- Keywords:
PTBP1;
Molecular mechanism;
Non-coding RNA;
Drug resistance
- From:
Cancer Research on Prevention and Treatment
2022;49(7):715-720
- CountryChina
- Language:Chinese
-
Abstract:
PTBP1, a widely-studied RNA binding protein, regulates mRNA splicing, translation, stability and localization. PTBP1 participates in a variety of ncRNA acting processes, affects tumorigenesis and tumor progression. In terms of tumor therapy, PTBP1 may act as a key factor to affect the target of targeted drugs and influence tumor resistance. This article reviews the role of PTBP1 in tumor and its research progress in tumor treatment.
