Application Progress of Metal-organic Frameworks in Tumors Therapy
10.3971/j.issn.1000-8578.2022.21.1158
- VernacularTitle:金属有机框架在肿瘤治疗中的应用进展
- Author:
Yang GUO
1
;
Suqing WU
;
Zhaohui WEN
Author Information
1. Department of Neurology and Brain Ultrasound, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China
- Publication Type:Research Article
- Keywords:
Metal-organic frameworks;
Tumor;
Photodynamic therapy;
Immunotherapy
- From:
Cancer Research on Prevention and Treatment
2022;49(5):472-477
- CountryChina
- Language:Chinese
-
Abstract:
Metal-organic frameworks (MOFs) are special materials formed by self-assembly of metal ions and organic ligands, with special physical and chemical properties, such as large specific surface area, excellent biocompatibility and strong pH sensitivity, etc. Through modification, they have synthesized nanomaterials with excellent performance, which have huge application prospects in treating tumors. This paper mainly reviews the properties of MOFs and their derived materials, and the application progress of MOFs in tumor drug-loaded therapy, photodynamic therapy and immunotherapy.
