Clinical Features and Prognostic Factors of Adenoid Cystic Carcinoma of Head and Neck
10.3971/j.issn.1000-8578.2022.21.1203
- VernacularTitle:头颈部腺样囊性癌的临床特点及预后影响因素
- Author:
Fengyang WU
1
;
Qiuji WU
;
Xiting YANG
;
Yahua ZHONG
Author Information
1. Department of Cancer Radiotherapy and Chemotherapy, Zhongnan Hospital, Wuhan University, Wuhan 430071, China
- Publication Type:Research Article
- Keywords:
Head and neck neoplasms;
Adenoid cystic carcinoma;
Prognosis;
Multivariate regression analysis
- From:
Cancer Research on Prevention and Treatment
2022;49(5):427-431
- CountryChina
- Language:Chinese
-
Abstract:
Objective To retrospectively analyze the clinical and pathological data of 48 patients with adenoid cystic carcinoma of the head and neck and screen out related factors that affect the patient's prognosis. Methods The overall survival rate of patients is used as the main indicator for observing prognosis. We selected 11 clinical and pathological factors as observation indicators that may have an impact on the survival and prognosis of patients. The relation between observation factors and the overall survival rate of patients was analyzed by Cox multivariate regression. Results The median follow-up time was 33.5(1-98) months. The 1-, 2- and 5-years overall survival rates were 95%, 91% and 87%. Local recurrence occurred in 14(29.2%) patients. Distant metastasis occurred in 22(45.8%) patients. Cox regression analysis showed that recurrence, distant metastasis and primary site were correlated with the overall survival rate of patients with head and neck adenoid cystic carcinoma (P < 0.05). Conclusion Adenoid cystic carcinoma is a relatively rare tumor of the head and neck with a low degree of malignancy. However, recurrence, distant metastasis and primary site have relatively great impact on the prognosis of patients.
