Clinical Characteristics and Prognostic Influence Factors of Patients with AIDS-related Malignant Tumor
10.3971/j.issn.1000-8578.2022.21.1056
- VernacularTitle:艾滋病合并恶性肿瘤患者临床特点及预后影响因素
- Author:
Haike LEI
1
;
Xiaosheng LI
;
Jieping LI
;
Jun LIU
;
Chunyan XIAO
;
Ying WANG
;
Wei ZHANG
;
Yao LIU
;
Yongzhong WU
Author Information
1. Department of Appointment and Follow-up Center, Chongqing University Cancer Hospital, Chongqing 400030, China
- Publication Type:Research Article
- Keywords:
HIV;
Malignant tumor;
Clinical features;
Survival;
Prognosis
- From:
Cancer Research on Prevention and Treatment
2022;49(5):412-417
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical characteristics and survival prognosis of patients with AIDS-related malignant tumor. Methods We retrospectively analyzed the data of 354 patients with AIDS-related malignant tumor. Univariate analysis was conducted by Log rank test and multivariate analysis was conducted by Cox proportional risk regression model. Results The average age of the patients was 54.10±12.96 years old. The ratio of male to female patients was 2.1:1. The number of patients with AIDS complicated with lymphoma was the most, accounting for 28.25%. The 1-, 3- and 5-year survival rates were 78.48%, 62.13% and 55.31%, respectively. Univariate analysis showed that there were statistical differences in prognosis of patients with different types of malignant tumor, age, gender, medical insurance type, number of admissions after diagnosis of AIDS, average length of stay, radiotherapy or not, leaving hospital according to medical advice. Multivariate analysis showed that gender, number of admissions after diagnosis of AIDS, average length of stay, proportion of out-of-pocket and leaving hospital according to medical advice were independent risk factors affecting the survival and prognosis of patients. Conclusion AIDS is easily complicated with lymphoma, lung cancer and cervical cancer. The patients received insufficient anti-tumor courses in hospital.
