Influence of LncRNA NKILA on Biological Behavior of Malignant Tumors and Related Mechanism
10.3971/j.issn.1000-8578.2022.21.0792
- VernacularTitle:LncRNA NKILA对肿瘤恶性生物学行为的影响及机制
- Author:
Yuqiao ZHAO
1
;
Guanglin LIU
;
Haicun WANG
;
Xin GAO
;
Xingming JIANG
;
Lang LIU
Author Information
1. Department of General Surgery, The 2nd Affiliated Hospital of Harbin Medical University, Harbin 150086, China
- Publication Type:Research Article
- Keywords:
Long non-coding RNA;
NKILA;
Tumors;
Malignant biological behavior
- From:
Cancer Research on Prevention and Treatment
2022;49(1):67-71
- CountryChina
- Language:Chinese
-
Abstract:
NKILA is a kind of newly-discovered lncRNA whose expression is aberrant in diverse malignant tumors. The existing researches have confirmed that NKILA participates in the occurrence and development of tumors mainly by regulating the NF-κB signaling pathway, and has significance to the cancer diagnosis, treatment and prognostic evaluation of patients. This article reviews the abnormal expressions and biological effects of NKILA, and the up- and down-stream mechanisms of NKILA regulating malignant biological behavior in different cancers.
