Improvement of memory function of mice by Funaoling Oral Liquid
- VernacularTitle:复脑灵口服液对小鼠记忆功能的改善作用及其机制
- Author:
Qiaru WANG
;
Hui LU
;
Jinxian XIE
;
Yongquan ZHANG
- Publication Type:Journal Article
- Keywords:
Funaoling Oral Liquid, memory, circulation, superoxide dismutase(SOD), mice
- From:
Chinese Journal of Rehabilitation Theory and Practice
2003;9(9):543-544
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the effect of Funaoling Oral Liquid on improving memory function of mice.Methods30 mice were injected with scopolamine 1mg/kg to make model of memory obstacle after treated by Funaoling Oral Liquid,piracetam or saline for 10 days.The escape test was used to measure the memory function.The blood circulation obstacle of the mice in mesentery was made by norepinephrine,and then, Funaoling Oral Liquid, Happy-hundred-year Oral Liquid and saline were given to observe the recovery time. The serum superoxide dismutase(SOD) activity in mice was measured after using different dosage of Funaoling Oral Liquid(75g/kg,37.5 g/kg and 18.75g/kg),piracetam or saline for 10 days.ResultsFunaoling Oral Liquid improved the memory function and blood circulation of mesentery significantly compared with that of the model(P<0.05 or P<0.01). The serum SOD activity in mice which was treated by Funaoling Oral Liquid 18.75g/kg were higher than that of model(P<0.05).ConclusionsThe Funaoling Oral Liquid can improve the memory and blood circulation of mice after injured,as well as to enhance the activity of SOD.
