Management of Adverse Reactions to Contrast Media and the Involvement of the Pharmaceutical Department in Hospitals: a Questionnaire Survey
- VernacularTitle:病院における造影剤副作用マネジメントと薬剤部門の関わり方に関する実態調査
- Author:
Sakura KONDO
1
;
Shinya SUZUKI
2
;
Tadamasa KAMIMURA
3
;
Hayato KIZAKI
1
;
Shungo IMAI
1
;
Satoko HORI
1
Author Information
- Keywords: contrast media; adverse reactions; pharmacist intervention; questionnaire survey
- From:Japanese Journal of Drug Informatics 2023;25(1):31-37
- CountryJapan
- Language:Japanese
- Abstract: Objective: Adverse reactions are sometimes induced by contrast media used for medical imaging and can be life-threatening. Thus, appropriate management is important for patient safety. The purpose of this study was to clarify the actual management of adverse reactions induced by contrast media in hospitals, the opportunities for intervention by hospital pharmacy departments and the attitudes of hospital pharmacists regarding the risk of adverse reactions.Methods: A self-administered questionnaire survey was conducted in the pharmacy departments of 16 hospitals (approximately 200 to 1,000 beds) located in the Tokyo metropolitan area of Japan. The survey asked about the presence or absence of internal rules or manuals regarding contrast media administration at each hospital, the management status of patients with risk factors for adverse reactions, the opportunities for interventions by pharmacists, and the opportunities for discussion regarding contrast media administration among pharmacists and other professionals.Results: Of the 16 hospitals, 10 responded to the questionnaires, and 7 of them had internal rules or manuals. These rules or manuals stipulated actions such as “do not administer contrast media” to patients with risk factor(s) for adverse reactions. For inpatients, there were opportunities for pharmacist interventions, such as drug management and guidance services and initial interviews upon hospital admission. However, for outpatients the opportunities for interventions were limited. At 5 of the 10 hospitals, pharmacists discussed contrast administration with physicians, radiologists, and other healthcare professionals.Conclusion: The present study reveal that many hospitals take great care in deciding on the administration of contrast media to patients at risk of adverse drug reactions. Our results indicate that the limited opportunities for “outpatient intervention" is an issue in the hospital pharmacy department's participation for proper use of contrast media.
