Analysis of Related Factors that Make Daikenchuto Useful for Constipation During Pregnancy
- VernacularTitle:妊娠中の便秘症に対して大建中湯が有効となる関連因子の解析 —後ろ向きコホート研究による検討—
- Author:
Takeshi NAKAYAMA
1
;
Aki MUKAI
2
;
Kyoko SUZUKI
2
;
Shuhei SO
2
;
Nao MURABAYASHI
3
;
Yoshimasa HORIKOSHI
3
;
Rui KOIZUMI
1
;
Hiroaki ITOH
1
Author Information
- Keywords: pregnancy; constipation; daikenchuto; constipation scale; history of surgery
- From:Kampo Medicine 2022;73(1):1-7
- CountryJapan
- Language:Japanese
- Abstract: The purpose of this study is to clarify factors related to the effect of daikenchuto on constipation during pregnancy. The subjects were 21 patients who had constipation during pregnancy and received 15 g/day of daikenchuto. Based on the constipation score that was created independently, the score values before administration, 2 weeks and 4 weeks after administration were retrospectively investigated. Furthermore, from the outcome of the oral status at 4 weeks, we divided the patients into 2 groups (12 in the improvement group and 11 in the non-improvement group), and attempted to extract factors that were considered to be related to efficacy. The total constipation score decreased significantly before and after administration of daikenchuto, and the concomitant symptoms of constipation scores were low, especially such as abdominal distension and abdominal pain. A comparison of the backgrounds of the improved group and the non-improved group revealed that the proportion of the patients with a history of surgery (laparotomy or laparoscopic surgery) was significantly higher in the improvement group. In addition, there were no particular problems with the pregnancy and delivery course of the 23 patients. Daikenchuto was considered to be highly effective against constipation during pregnancy, especially in pregnant women with a history of surgery.
