Advances in clinical diagnosis and treatment of drug-induced liver injury in children.
10.3760/cma.j.cn501113-20220309-00105
- Author:
Xiao Rong PENG
1
;
Yu Nan CHANG
1
;
Tao QIN
1
;
Ting Ting SHANG
1
;
Hong Mei XU
1
Author Information
1. Department of Infectious Disease, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing 400014, China.
- Publication Type:Journal Article
- Keywords:
Children;
Clinical feature;
Diagnosis;
Drug-induced liver injury;
Treatment
- MeSH:
Child;
Humans;
Chemical and Drug Induced Liver Injury/therapy*;
Drug-Related Side Effects and Adverse Reactions;
Liver/pathology*;
Risk Factors
- From:
Chinese Journal of Hepatology
2023;31(4):440-444
- CountryChina
- Language:Chinese
-
Abstract:
Drug-induced liver injury (DILI) is one of the most common adverse drug reactions that may seriously threaten the health of children and is receiving increasing clinical attention day by day. There is still no independent diagnosis and treatment guideline for DILI in children, but its clinical features are not completely similar to those in adults. This article reviews the epidemiology, clinical features, diagnosis, and treatment progress in order to provide a reference for the management of DILI in children.