Comparative analysis of clinical diagnosis and treatment guidelines for drug-induced liver injury at home and abroad.
10.3760/cma.j.cn501113-20220810-00415
- Author:
Rong Rong LI
1
;
Meng LI
1
;
Qiong LUO
1
;
Xin SUN
2
;
Cheng Hai LIU
3
Author Information
1. Institute of Liver Diseases, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
2. Institute of Liver Diseases, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China Shanghai Key Laboratory of Traditional Chinese Clinical Medicine, Shanghai 201203, China.
3. Institute of Liver Diseases, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China Shanghai Key Laboratory of Traditional Chinese Clinical Medicine, Shanghai 201203, China Key Laboratory of Liver and Kidney Diseases, Ministry of Education, Shanghai 201203, China.
- Publication Type:Journal Article
- Keywords:
Clinical guidelines;
Diagnosis;
Drug-induced liver injury;
Herb-induced liver injury;
Therapy
- MeSH:
Humans;
Chemical and Drug Induced Liver Injury/therapy*;
Medicine, Chinese Traditional
- From:
Chinese Journal of Hepatology
2023;31(4):433-439
- CountryChina
- Language:Chinese
-
Abstract:
Drug-induced liver injury influencing factors are complex and have diverse clinical manifestations. Simple and reliable diagnostic methods are still deficient, and further classification of toxicological mechanisms is required. There are numerous pertinent discrepancies between domestic and international guidelines aimed at drug-induced liver injury diagnosis and treatment, with partial to no consensus on the content. The American Gastroenterological Association's 2021 Clinical Guidelines, the Asia-Pacific Association for the Study of the Liver's 2021 Consensus Guidelines, the Council for International Organizations of Medical Sciences' 2020 International Consensus, the European Society's Hepatology Committee's 2019 Clinical Practice Guidelines, and the 2015 Chinese Medical Association Guidelines are five influential clinical guidelines on drug-induced liver injury at home and abroad. The epidemiology, risk factors, diagnosis and evaluation, treatment management, and other contents, particularly traditional Chinese medicine, were compared and analyzed using other relevant consensus opinions or guidelines in order to improve understanding and provide a reference for clinical diagnosis and treatment of drug-induced liver injury.
