Advances in the regulation of craniomandibular regeneration by topical application of parathyroid hormone.
10.3760/cma.j.cn112144-20220904-00475
- Author:
Mian Mian DUAN
1
;
Zheng Long TANG
1
Author Information
1. Department of Oral and Maxillofacial Surgery, Affiliated Stomatological Hospital of Guizhou Medical University, Guiyang 550004, China.
- Publication Type:Journal Article
- From:
Chinese Journal of Stomatology
2023;58(7):699-704
- CountryChina
- Language:Chinese
-
Abstract:
Parathyroid hormone (PTH) is a polypeptide molecule synthesized and secreted by parathyroid principal cells. It is an important hormone to maintain the balance of calcium and phosphorus metabolism in the body. It has the dual function of promoting bone formation and bone resorption. In clinic, it promotes osteogenesis by intermittent low-dose subcutaneous injection. In order to avoid the problems of subcutaneous injection, such as poor patient compliance, low utilization of target organs and pain at the injection site, the local application of PTH has attracted much attention in recent years. However, how to realize the local application of PTH and the effect of the local application need to be confirmed by more experiments. This article reviews the local application of PTH and the promotion of jaw regeneration in recent years, in order to provide reference for the local application and research of PTH.
