The 501st case: elevated blood glucose, chronic pancreatitis, and post- pancreatoduodenectomy malnutrition.
10.3760/cma.j.cn112138-20221120-00870
- Author:
An SONG
1
;
Rui ZHANG
1
;
Yue CHI
1
;
Hua Bing ZHANG
1
Author Information
1. Department of Endocrinology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Translational Medicine Center, Key Laboratory of Endocrinology, Ministry of Health, Beijing 100730, China.
- Publication Type:Journal Article
- MeSH:
Male;
Humans;
Middle Aged;
Blood Glucose;
Diabetes Mellitus, Type 2/complications*;
Pancreaticoduodenectomy/adverse effects*;
Pancreatitis, Chronic/complications*;
Malnutrition/complications*
- From:
Chinese Journal of Internal Medicine
2023;62(7):891-895
- CountryChina
- Language:Chinese
-
Abstract:
A 50-year-old man with a 15-year history of elevated blood glucose and an approximately 2-year history of diarrhea was admitted to the Peking Union Medical College Hospital. The initial diagnosis was type 2 diabetes. After repeated pancreatitis and pancreatoduodenectomy, severe pancreatic endocrine and exocrine dysfunction including alternating high and low blood glucose and fat diarrhea occurred. Tests for type 1 diabetes-related antibodies were all negative, C-peptide levels were substantially reduced, fat-soluble vitamin levels were reduced, and there was no obvious insulin resistance. Therefore, a diagnosis of pancreatic diabetes was clear. The patient was given small doses of insulin and supplementary pancreatin and micronutrients. Diarrhea was relieved and blood glucose was controlled. The purpose of this article is to raise clinicians' awareness of the possibility of pancreatic diabetes after pancreatitis or pancreatic surgery. Timely intervention and monitoring may reduce the occurrence of complications.
