Advances in the study of postpancreatectomy acute pancreatitis.
10.3760/cma.j.cn112139-20230221-00075
- Author:
Hao Min CHEN
1
;
Meng Hua DAI
1
Author Information
1. Department of General Surgery,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100730,China.
- Publication Type:Journal Article
- MeSH:
Humans;
Pancreatitis/complications*;
Retrospective Studies;
Acute Disease;
Pancreas;
Postoperative Complications/etiology*;
Pancreatic Fistula/etiology*;
Pancreaticoduodenectomy/adverse effects*
- From:
Chinese Journal of Surgery
2023;61(7):609-613
- CountryChina
- Language:Chinese
-
Abstract:
Postpancreatectomy acute pancreatitis (PPAP) is an acute inflammation of the remnant pancreas in the early postoperative period caused by a variety of factors. With the progress of related research,PPAP has been confirmed as an independent risk factor for many severe complications such as postoperative pancreatic fistula. In some cases, it progresses to necrotizing PPAP, increasing the risk of mortality. Currently, the International Study Group for Pancreatic Surgery has standardized and graded PPAP as an independent complication, taking into account factors including serum amylase, radiological features, and clinical impact. This review summarizes how the concept of PPAP was proposed, as well as the latest progress in the research related to its etiology, prognosis, prevention, and treatment. However, given the large heterogeneity of relevant studies and the fact that they were mostly retrospective, in the future, it is necessary to place more emphasis on PPAP and elucidate the problems through more standardized studies to optimize strategies for the prevention and management of complications after pancreatic surgery.
