A case-control study on the association between a healthy lifestyle and obesity among adult twins in Shanghai.
10.3760/cma.j.cn112338-20221114-00970
- VernacularTitle:上海市成年双生子健康生活方式与肥胖的关联研究
- Author:
Rong Fei ZHOU
1
;
Zhen Ni ZHU
2
;
Zheng Yuan WANG
2
;
Jia Jie ZANG
2
;
Xiao Dong JIA
3
;
Jun LYU
4
;
Li Ming LI
4
;
Fan WU
1
Author Information
1. School of Public Health, Fudan University, Shanghai 200032, China.
2. Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China.
3. Shanghai Chemical Industry Park Medical Center, Shanghai 201507, China.
4. Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.
- Publication Type:Twin Study
- MeSH:
Adult;
Humans;
Case-Control Studies;
China/epidemiology*;
Healthy Lifestyle;
Obesity/epidemiology*;
Obesity, Abdominal/epidemiology*;
Overweight/epidemiology*;
Twins, Monozygotic
- From:
Chinese Journal of Epidemiology
2023;44(6):862-867
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the associations between the numbers of healthy lifestyles and overweight/obesity and abdominal obesity in adult twins in Shanghai. Methods: Based on the Shanghai Twin Registry System Phase Ⅱ survey data in 2017-2018, a case-control study was conducted to analyze the association between healthy lifestyles and obesity and further adjusted for confounders by a co-twin control study. Results: A total of 7 864 adult twins (3 932 pairs) were included. In the co-twin case-control analysis for monozygotic twins, compared with participants with 0 to 2 healthy lifestyles, those with 3 and 4 to 5 healthy lifestyles had a 49% (OR=0.51, 95%CI: 0.28-0.93) and 70% (OR=0.30, 95%CI: 0.13-0.69) lower risk of overweight/obesity, respectively, and a 17% (OR=0.83, 95%CI: 0.44-1.57) and 66% (OR=0.34, 95%CI: 0.14-0.80) lower risk of abdominal obesity, respectively. For each additional healthy lifestyle, the risk of developing overweight/obesity was reduced by 41% (OR=0.59, 95%CI: 0.42-0.85), and the risk of developing abdominal obesity was reduced by 37% (OR=0.63, 95%CI: 0.44-0.90). Conclusion: An increasing number of healthy lifestyles was associated with a marked decreased risk for both overweight/obesity and abdominal obesity.