Research progress on the effectiveness of smallpox vaccination against mpox virus infection.
10.3760/cma.j.cn112338-20221102-00934
- VernacularTitle:接种天花疫苗对猴痘病毒感染的保护作用研究进展
- Author:
Yun Shao XU
1
;
Ming Yue JIANG
1
;
Yan Lin CAO
1
;
Yan Xia SUN
1
;
Qiang Ru HUANG
1
;
Wei Zhong YANG
1
;
Lu Zhao FENG
1
Author Information
1. School of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
- Publication Type:Journal Article
- MeSH:
Humans;
Smallpox/epidemiology*;
Monkeypox/drug therapy*;
Smallpox Vaccine/therapeutic use*;
Vaccination;
Immunity
- From:
Chinese Journal of Epidemiology
2023;44(4):673-676
- CountryChina
- Language:Chinese
-
Abstract:
With the expansion of mpox virus infection from endemic to a global epidemic in 2022, the WHO declared that the mpox event constituted a Public Health Emergency of International Concern. Due to the high degree of gene sequence similarity among orthopox viruses and cross-reactive antibodies induced by orthoviruses, smallpox vaccination may affect the immune response induced by mpox virus infection. The analysis of the protective effects of smallpox vaccination against mpox virus infection will help define the focus of prevention and control. In this review, we clarify the protection of the smallpox vaccine against mpox virus infection by analyzing the correlation between smallpox vaccination, immune response status, and clinical data and providing evidence for the prevention, control, and strategies of mpox epidemics.
