Application of microfluidic assays for cardiovascular disease markers in early warning and rapid diagnosis.
10.3760/cma.j.cn112150-20220916-00901
- VernacularTitle:心血管疾病标志物微流控检测在早期预警与快速诊断中的应用
- Author:
Tai Ju CHEN
1
;
Rui Ning LIU
2
;
Hong ZHANG
3
;
Hua Ming MOU
4
;
Yang LUO
1
Author Information
1. Center for Intelligent Laboratory and Molecular Medicine, School of Medicine Chongqing University,Chongqing 400030,China Key Laboratory of Birth Defects and Reproductive Health of National Health and Family Planning Commission,Chongqing 400020,China.
2. Center for Intelligent Laboratory and Molecular Medicine, School of Medicine Chongqing University,Chongqing 400030,China.
3. Key Laboratory of Birth Defects and Reproductive Health of National Health and Family Planning Commission,Chongqing 400020,China Laboratory Medicine Center of the Second Hospital of Shandong University,Jinan 250033,China.
4. Department of Cardiovascular Medicine,Three Gorges Hospital Affiliated to Chongqing University,Chongqing 404100,China.
- Publication Type:Journal Article
- MeSH:
Humans;
Microfluidics;
Cardiovascular Diseases/diagnosis*;
Biomarkers;
Early Diagnosis
- From:
Chinese Journal of Preventive Medicine
2023;57(7):1115-1123
- CountryChina
- Language:Chinese
-
Abstract:
Cardiovascular disease is a major threat to human health and has become the leading cause of death worldwide; therefore, early diagnosis and treatment are of great value. Due to its miniaturization, integration, and ease of operation, microfluidic technology enables the rapid, multi-target detection of cardiovascular disease markers and significantly facilitates the early and rapid diagnosis of cardiovascular disease. This article reviews the research progress of microfluidics in cardiovascular disease detection, analyzes its advantages and weaknesses in the rapid detection of protein, lipid, and nucleic acid biomarkers, hopes to provide a reference to promote the quick detection technology of cardiovascular disease, and thus proposes new considerations for the early management of cardiovascular disease.
